Mammography is a diagnostic imaging procedure of the breast to detect and evaluate breast disease. Mammography is widely used as a screening method and plays a key role in early breast cancer detection.
The screening mammography is used to detect breast changes in women who have no signs or symptoms or noticed breast abnormalities. The goal is to detect a breast tumor before any clinical signs are observable.
A diagnostic mammography is used to investigate suspicious breast changes, such as a breast lump, an unusual skin appearance, breast pain, nipple thickening or nipple discharge.
A breast screening or standard mammography requires two mammograms from different angles of each breast including craniocaudal view and mediolateral view. Additional images can be made from other angles or focus on microcalcifications or other suspicious areas.
A mammogram is created by special mammography equipment with long wavelength of the used x-rays. Film-screen mammography is still the most widely used technology, but the state of the art technique is digital mammography. Conventional x-ray equipment was used to produce mammograms until dedicated mammography equipment became available in the late 1960s. Film-screen mammography and xeromammography, introduced in the early 1970s, used lower radiation doses and produced sharper mammograms. The second generation of mammography systems has been introduced in the early 1980s. Chief disadvantages of analog mammography include the labor-intensive handling of the cassettes, relatively slow processing time, the lack of a direct interface to the x-ray system, and no post processing possibilities.
Mammograms of high quality should be done with the lowest radiation dose as possible. Adequate breast compression is important due to shortening of the exposure times, immobilization of the breast, reduction of motion and blurring and prevention of overpenetration by means of equalizing breast thickness.
Further breast imaging procedures include breast ultrasound and breast MRI.

A bone scan or bone scintigraphy is used to in evaluate diseases of the skeletal system. Scintigraphic whole body bone imaging is a highly sensitive method to show changes in bone metabolism. Increased metabolic activity is seen as a hot spot.
The study requires the injection of a 99mTc-labeled radiopharmaceutical (most commonly methylene diphosphonate (MDP), hydroxymethylene diphosphonate (HMDP) or hydroxyethylene diphosphonate (HDP)). The activity administered for bone scanning is around 500 MBq (300-1100 MBq, 8-30 mCi), depending on age and weight of the patient. After 2-5 hours, the emitted gamma rays are detected by gamma cameras. The produced planar images include anterior and posterior views of the skeleton.
Multiphase bone scintigraphy is used to differentiate a bone process from tissue pathology. In some cases additional SPECT imaging is helpful to better characterize the presence, location and extent of disease.

(Computed tomography number) The CT number is a selectable scan factor based on the Hounsfield scale. Each elemental region of the CT image (pixel) is expressed in terms of Hounsfield units (HU) corresponding to the x-ray attenuation (or tissue density).
CT numbers are displayed as gray-scale pixels on the viewing monitor. White represents pixels with higher CT numbers (bone). Varying shades of gray are assigned to intermediate CT numbers e.g., soft tissues, fluid and fat. Black represents regions with lower CT numbers like lungs and air-filled organs.

A computed tomography (CT) scanner is used to create cross-sectional slices of different objects. The medical version of CT system scans the human body for tumors or other abnormalities, other versions are used for non-destructive testing in the industry.
The CT imaging system includes the moveable gantry and patient table or couch. The gantry is a frame that contains the x-ray source, collimators, filters, detectors, a data acquisition system (DAS), rotational components including slip ring systems and all associated electronics. The x-ray tube and detector system are mounted opposite each other, allowing a rapid and synchronous rotation around the patient table.
In older CT scanners a small generator supplied power to the x-ray tube and the rotational components via cables for operation. Up to the 4th generation the CT tube and detectors rotate together around the patient for each slice. CT systems with slip ring technology (the x-ray tube rotates around a stationary ring of detectors) operate without cables and provides continuous rotation of the gantry components without interference of cables. Spiral CT scanners work with a continuous table movement while the x-ray tube is rotating around the patient.

Overview about CT scanner generations:
See also Contrast Media Injector, Dual-Head CT Power Injector, Syringeless CT Power Injector.

A calibration is a correction procedure that determines the relationship between the measured output of a system and the reference standard. Calibration procedures include scanning air or an appropriate test phantom.
The calibration of a CT system takes account of variations in beam intensity or detector efficiency in order to achieve best homogeneity within the field of view and the accuracy of CT numbers.

See also Calibration Factor and Acceptance Checking.