Contrast is the relative difference of intensities in two adjacent regions of an image. When referring to computed tomography (CT), contrast is defined as a difference in Hounsfield units between structures. The measurement of contrast resolution in CT imaging involves determining how easy it is to differentiate tissues whose CT density is similar to that of their surroundings. An image lacks contrast when there are no sharp differences between black and white. Brightness refers to the overall lightness or darkness of an image.
The contrast between air, soft tissue, and bones in x-ray and CT images is based on their different absorption of x-rays. Differences in tissue density, thickness and changes of the x-ray spectrum have consequences for image contrast, image noise as well as patient dose.
Optimized tube current, collimation, pitch and image reconstruction improves the contrast. Higher image contrast is produced by increased slice thickness, smaller matrix, and large field of view which results in large voxel size; high mAs to reduce noise; low pass filter.

See also Contrast Enhanced Computed Tomography.

In medical imaging, resolution is the ability to distinguish two adjacent objects and a measurement of image quality. The resolution of tomographic images is a function of slice thickness, field of view (FOV) and matrix size. The resolution in plane is a function of FOV / matrix size.

The resolution element has the size of the smallest spatially resolved region in an image. It may be anisotropic, e.g. with an asymmetric acquisition matrix or slice thickness, and may be larger than the pixel or voxel.

A voxel is a volume element (volumetric pixel) representing a value in the three dimensional space (expressed in units of mm³), corresponding to a pixel for a given slice thickness. Voxels are frequently used in the visualization and analysis of medical data. The CT pixel intensity is proportional to the signal intensity of the appropriate voxel. Voxels are associated with CT numbers.

(CT or CAT scan) Computed tomography is a diagnostic imaging technique, previously also known as computerized axial tomography (CAT), computer-assisted tomography (CAT), computerized tomographic imaging, and reconstructive tomography (RT).
A CT scan is based on the measurement of the amount of energy that a tissue absorbs as a beam of radiation passes through it from a source to a detector. As the patient table moves through the CT scanner, the CT tube rotates within the circular opening and the set of x-ray detectors rotate in synchrony. The narrow, fan-shaped x-ray beam has widths ranging from 1 to 20 mm. The large number of accurate measurements with precisely controlled geometry is transformed by mathematical procedures to image data. Corresponding to CT slices of a certain thickness, a series of two-dimensional cross-sectional images is created.
A CT is acquired in the axial plane, while coronal and sagittal images can be rendered by computer reconstruction. Although a conventional radiography provides higher resolution for bone x-rays, CT can generate much more detailed images of the soft tissues. Contrast agents are often used for enhanced delineation of anatomy and allow additional 3D reconstructions of arteries and veins.
CT scans use a relatively high amount of ionizing radiation compared to conventional x-ray imaging procedures. Due to widespread use of CT imaging in medicine, the exposure to radiation from CT scans is an important issue. To put this into perspective, the FDA considers the risk of absorbed x-rays from CT scans to be very small. Even so, the FDA recommends avoiding unnecessary exposure to radiation during diagnostic imaging procedures, especially for children.
CT is also used in other than medical fields, such as nondestructive testing of materials including rock, bone, ceramic, metal and soft tissue.

See also Contrast Enhanced Computed Tomography.