Radiation can ionize matter caused by the high energy which displaces electrons during interactions with atoms. In the electromagnetic spectrum higher frequency ultraviolet radiation begins to have enough energy to ionize matter.
Examples of ionizing radiation include alpha particles, beta particles, gamma rays, x-rays, neutrons, high-speed electrons, high-speed protons, and other particles capable of producing ions by direct or secondary processes in passage through tissues.
Damage of living tissue results from the transfer of energy to atoms and molecules in the cellular structure. Ionized cells have to repair themselves to remain alive. Generally, healthy cells have a higher capability to repair themselves than cancer cells.

Biological effects of ionizing radiation exposure:
Ionizing radiation are used in a wide range of facilities, including health care, research institutions, nuclear reactors and their support facilities, and other manufacturing settings. These radiation sources can pose a serious hazard to affected people and environment if not properly controlled.

See also Radiation Safety, Controlled Area, Radiotoxicity and As Low As Reasonably Achievable.

(LOCM) Low-osmolar contrast media have a wide range of indications due to their lower side effects. The type of contrast media is an important risk factor for an adverse reaction.
LOCM have not completely replaced contrast media with higher osmolality due to their higher cost. Guidelines of professional organizations give recommendations for the selective use of low-osmolar contrast media for certain high-risk patients.
There are ionic and nonionic iodinated contrast materials with low osmolality available:
An adverse reaction occurs in low-risk patients who receive conventional ionic contrast agents more often than in high-risk patients who receive nonionic LOCM.

See also Contrast Enhancement, Biliary Contrast Agents, Safety of Contrast Agents and Contrast-Induced Nephropathy.

Multi-head contrast media injectors offer flexible contrast media management, simplified workflows and increased patient safety.
Contrast delivery is much more controlled and efficient when using a dual-head CT power injector. These medical devices are needed to enable the short imaging times typical of multidetector computed tomography (CT) scanners.
Triple-head injectors allow selection of a second contrast agent when two different contrast agents are used, or switching to full contrast agent containers when two identical contrast agents are used.

See also Contrast Media Injector, Syringeless CT Power Injector, Single-Head Contrast Media Injector, CT Power Injector.

Different stages of testing drugs in humans, from first application in humans through limited and broad clinical tests, to postmarketing studies. Preclinical trials are the testing in animals.

Radiation shielding is the process of limiting the penetration of radiation into the environment, by blocking with a barrier made of impermeable material. This protective barrier is usually formed of a material with high density, for example lead that absorbs the radiation.
Radiation sources are self-shielded with absorbing material incorporated into the equipment, adjacent to the source to reduce stray radiation to the surrounding area below dose limits.
Rooms with x-ray or other radiation equipment are additionally shielded with lead-lined walls to reduce the radiation exposure to humans within the facility. The amount of shielding required to protect against different kinds of radiation depends on how much energy they have. The shielding calculations are based on the half value layer of the primary radiation beam. Sufficient half value layers of shielding are calculated to reduce the radiation exposure outside the room to reasonable levels.
Personal shielding requirements depending on the type of radiation:
See also Radiation Safety.