Radiotoxicity refers to radioactive materials that are toxic to living cells or tissues. Radiotoxicity results from the type of radiation, the radioactive half-life of the used radionuclide, the biological half-life in the tissue and the radioactivity absorbed in the organ. Radiotoxic substances can be collected following ingestion, inhalation and absorption.

Radiation can ionize matter caused by the high energy which displaces electrons during interactions with atoms. In the electromagnetic spectrum higher frequency ultraviolet radiation begins to have enough energy to ionize matter.
Examples of ionizing radiation include alpha particles, beta particles, gamma rays, x-rays, neutrons, high-speed electrons, high-speed protons, and other particles capable of producing ions by direct or secondary processes in passage through tissues.
Damage of living tissue results from the transfer of energy to atoms and molecules in the cellular structure. Ionized cells have to repair themselves to remain alive. Generally, healthy cells have a higher capability to repair themselves than cancer cells.

Biological effects of ionizing radiation exposure:
Ionizing radiation are used in a wide range of facilities, including health care, research institutions, nuclear reactors and their support facilities, and other manufacturing settings. These radiation sources can pose a serious hazard to affected people and environment if not properly controlled.

See also Radiation Safety, Controlled Area, Radiotoxicity and As Low As Reasonably Achievable.