Radiopaque materials are not penetrable by radiation or impede x-rays. Radiopaque substances appear white on radiographic images.

See also Contrast Agents.

Radiographic contrast media (RCM) contributes important information to the diagnostic process. Actual contrast agents are safe drugs. Adverse reactions are rare, the incidence and severity of side effects decrease with the use of nonionic and low-osmolar contrast media. Adverse reactions are diverse, ranging from mild physiological disturbances to very rare life-threatening anaphylactic or anaphylactoid reactions. Users of contrast agents must be aware of the risk factors and be prepared to promptly manage adverse effects.
Side effects that may occur with intravascular administration of contrast agents are also possible after administration by other paths. Increased risk to an adverse reaction includes patients with a history of a previous reaction to a contrast medium, a known sensitivity to iodine, or a known clinical hypersensitivity (bronchial asthma, hay fever, and food allergies).

See also Contrast-Induced Nephropathy, Iodide-Induced Hyperthyroidism and Idiosyncratic Reactions.

Different types of screens are used in medical imaging. The intensifying screen or a pair of screens is used with x-ray film in radiography. Fluorescent screens coated with phosphor crystals emit light when exposed to radiation.

Tomography is imaging by sections or sectioning to obtain images of slices through objects like the human body. Tomography is derived from the Greek words 'to cut or section' (tomos) and 'to write' (graphein). A device used in tomography is called a tomograph, while the image produced is a tomogram.
The first medical applications utilized x-rays for images of tissues based on their x-ray attenuation coefficient. The mathematical basis for tomographic imaging was laid down by Johann Radon. This type of imaging is used in different medical applications as for example computed tomography, ultrasound imaging, positron emission tomography and magnetic resonance imaging (MRI) also called magnetic resonance tomography (MRT).
Conventional x-ray tomographic techniques show organ structures lying in a predetermined plane (the focal plane), while blurring the tissue structures in planes above and below by linear or complex geometrical motion of the x-ray tube and film cassette.
Basically, computed tomography is the reconstruction of an image from its projections. In the strict sense of the word, a projection at a given angle is the integral of the image in the direction specified by that angle. The CT images (slices) are created in the axial plane, while coronal and sagittal images can be rendered by computer reconstruction.

See also Zonography, Computed or Computerized Axial Tomography, Resolution Element, Radiographic Noise, Intravenous Pyelogram.

X-rays are a part of the electromagnetic spectrum. X-rays and gamma rays are differentiated on the origin of the radiation, not on the wavelength, frequency, or the energy. X-rays are emitted by electrons outside the nucleus, while gamma rays are emitted by the nucleus. X-rays have wavelengths in the range of about 1 nanometer (nm) to 10 picometer (pm), frequencies in the range of 10^-16 to 10^-20 Hertz (Hz) and photon energies between 0.12 and 120 kilo electron Volt (keV). The energy of rays increase with decreased wavelengths. X-rays with energies between 10 keV and a few hundred keV are considered hard X-rays. The cutoff between soft or hard X-rays is around a wavelength of 100 pm.
Because of their short wavelength, X-rays interact little with matter and pass through a wide range of materials. These interactions occur as absorption or scattering;; primary are the photoelectric effect, Compton scattering and, for ultrahigh photon energies of above 1.022 mega electron Volt (MeV), pair production.
X-rays are produced when high energy electrons struck a metal target. The kinetic energy of the electrons is transformed into electromagnetic energy when the electrons are abruptly decelerated (also called bremsstrahlung radiation, or braking radiation) similar to the deceleration of the circulating electron beam in a synchrotron particle accelerator. Another type of rays is produced by the inner, more tightly bound electrons in atoms;; frequently occurring in decay of radionuclides (characteristic radiation, gamma ray, beta ray). The energy of an X-ray is equivalent to the difference in energy of the initial and final atomic state minus the binding energy of the electron.
Wilhelm Conrad Roentgen discovered this type of rays (also called Roentgen-rays) in 1895 and realized that X-rays penetrate soft tissue but are absorbed by bones, which provides the possibility to image anatomic structures; the first type of diagnostic imaging was established. Radiographic images are based on this difference in attenuation for tissue and organs of different density. Today ionizing radiation is widely used in medicine in the field of radiology.

See also Exposure Factors, X-Ray Tube, and X-Ray Spectrum.