A biopsy is a procedure in which tissue samples are collected. This can be done with a needle, which is inserted into the abnormal area.
An example is the needle breast biopsy. Needle biopsies are usually guided by different imaging techniques like ultrasound, computed tomography, or magnetic resonance imaging. Stereotactic-assisted breast biopsies use computer maps to guide the needle. The location of the breast lump is provided from digital mammograms taken from two angles.
The cells can be removed and examined under a microscope to determine whether the abnormality is cancerous.

See also CT Guided Biopsy.

Breast imaging methods include mammography (mammogram), ultrasound, breast MRI, positron emission tomography, xeromammography, diaphanography and thermography.
Mammography is widely used as a screening method and diagnostic tool for breast cancer detection or evaluation of breast disease. Digital mammography takes multiple thin digital image 'slices' through the breast, which provides higher potential to see a small mass within dense tissue. The mammography quality standards act guarantees a high image quality.
Breast ultrasound (also called ultrasonography) should only be used as an additional imaging modality to evaluate specific breast abnormalities, especially to differentiate cystic from solid masses. Ultrasound is also used to guide needle breast biopsies.
Magnetic resonance imaging (MRI) is useful for breast MRI screening in cases of high cancer risk. In addition, multifocal breast cancer can be missed by standard practice mammography and can be early detected with breast MRI.

A cinefluorography produces a movie (cine) film from an image intensifier during x-rays examinations (often called videofluorography, cineradiography or cine). Cinefluorography is always monitored on the TV screen normally used for fluoroscopy. The image from the output screen of the image intensifier is split with a semi-transparent mirror into two output ports; one leading to the movie camera and the other to the fluoroscopy camera. Most of the light is directed to the cine camera. The image on the monitor does not suffer in quality due to the fact that the tube current for cinefluorography is about 100 times higher than for common fluoroscopy.
The x-ray generator pulses are synchronized with the movements of the cine camera, so that no x-rays are emitted when the film is moved forward to the next frame. The needed very accurate synchronization of the x-ray generator can be achieved by use of high voltage switching in the secondary circuit of the constant potential x-ray generator, by starting and stopping the inverter in a medium frequency generator or by using a grid controlled x-ray tube.

Chemical, usually ammonium thiosulfate, added to the fixer to remove undeveloped silver bromine from the film emulsion.

A tomographic imaging plane, perpendicular to the ground, the coronal plane separates the anterior from the posterior part (the front from the back).