Radiation can ionize matter caused by the high energy which displaces electrons during interactions with atoms. In the electromagnetic spectrum higher frequency ultraviolet radiation begins to have enough energy to ionize matter.
Examples of ionizing radiation include alpha particles, beta particles, gamma rays, x-rays, neutrons, high-speed electrons, high-speed protons, and other particles capable of producing ions by direct or secondary processes in passage through tissues.
Damage of living tissue results from the transfer of energy to atoms and molecules in the cellular structure. Ionized cells have to repair themselves to remain alive. Generally, healthy cells have a higher capability to repair themselves than cancer cells.

Biological effects of ionizing radiation exposure:
Ionizing radiation are used in a wide range of facilities, including health care, research institutions, nuclear reactors and their support facilities, and other manufacturing settings. These radiation sources can pose a serious hazard to affected people and environment if not properly controlled.

See also Radiation Safety, Controlled Area, Radiotoxicity and As Low As Reasonably Achievable.

Isomers are nuclides with the same number of neutrons and protons of a given element in different states of excitation. Most of these unstable isomers decay very quickly (~ 10^-12 seconds).
They are characterized in the chemical formula by an m (e.g. Tc-99m).

See also Isomeric Transition.

If a nucleus still has excess energy after attempts of stabilization, it can emit energy without changing the number of protons or neutrons. This process is named isomeric transition. One way of isomeric transition is the emission of a gamma rays, the other competing way is internal conversion, where the excess energy of the nucleus must exceed the binding energy of an electron, which then will be ejected from the atom.

See also Decay, Gamma Radiation and Internal Conversion.

Isotopes of a given element have the same number of protons but a different number of neutrons in the core. Isotopes have the same electronic structure as the given element and thus have a nearly identical chemical behavior. Larger elements tend to have more stable isotopes than smaller ones.
For example, I123, I125 and I131 are isotopes of iodine; they have a different mass number.

The mass number is the total number of protons and neutrons (also total nucleon) in the nucleus.

See also Atomic Mass Unit, Atomic Mass.