Usually, magnification is the enlargement of an area by interpolation after the reconstruction of an image. Magnification does not provide more information, but allows a better view of certain object details. A zoom reconstruction is based on the raw data of the scan. Magnification software enlarges an image by mapping one pixel onto an n x n array of screen pixels (pixel stretching).
Other types of magnification include electron-optical, geometric, the product of geometric and the electron-optical magnification and enlargement by imaging procedures.
Electron-optical magnification is the ratio of the dimension of the detector input image and the size of the image on the screen. This ratio is determined by all electronic and optical imaging processes of the image chain, provided that one camera pixel is mapped onto accurately one monitor pixel.
Geometric magnification occurs in x-ray images when the focal spot is theoretically assumed to be a point and not an area. For nanofocus and microfocus radiographic systems, the focus-to-detector (film) distance and the focus-to-object (film) distance defines the geometric magnification.
The total magnification is the product of the electron-optical and geometric magnification. Possible magnifications are up to a factor of 26,000.
Magnification procedures in medical imaging are usually produced by extended distance between the subject and the image receptor.

The digital mammography is an electronic imaging procedure of the breast. The number of breast imaging facilities equipped with digital mammography (also called computed radiography mammogram (CRM), CR mammogram) is growing due to a number of advantages.
Digital images can be stored directly in a picture archiving and communication system (PACS) and allows the printing, enhancement, magnification, or brightness and contrast manipulation for further evaluation. The sensitivity of digital mammography compared to film mammography is better in women with dense breasts, a population at higher risk for breast cancer, due to these post processing possibilities.
'The American College of Radiology's (ACR) Imaging Network found that digital mammography detected up to 28 percent more cancers than film-screen mammography in women age 50 and younger, premenopausal and perimenopausal women, and women with dense breasts, as reported in October 2005 in the New England Journal of Medicine.'

Advantages of digital mammography:
Existing mammography equipment can be converted to 'digital' operation, which allows cost savings compared to integrated digital mammography systems.

See also Breast MRI.

(DR) Digital radiography uses a special electronic x-ray detector, which converts the radiographic image into a digital picture for review on a computer monitor. The digital image is then stored and can be post processed by changing the magnification, orientation, brightness, and contrast. Digital radiography (also called direct radiography) is a progressive development of computed radiography (CR).
These advantages can lead to fewer 'recalls' (repeated x-ray images) including a lower radiation dose than analog or conventional radiography. DR and CR systems use no chemicals to process the x-ray images and the hazardous materials and waste associated with film development are eliminated.

Advantages of digital radiography compared with conventional radiography:

The focal spot is the point where the electron beam impinges on the tube anode and from which x-rays are emitted. The size of the focal spot is determined by the size of the filament and cathode, which is determined by the manufacturer.
Most x-ray tubes have more than one focal spot size. The size of the focal spot has influence on spatial resolution. The smaller the focal spot, the better the limiting spatial resolution of the x-ray system, especially in magnification mammography. The use of a small focal spot concentrates heat onto a smaller portion of the anode therefore, more heat is generated and a longer cooling time is necessary.

In nuclear medicine a hot spot describes a strong activity enrichment in one or more ranges of the organ or body part which is examined.
A pinhole collimator may be used if images of a hot spot and the surrounding with very high resolution are necessary. Zoom magnification or a converging collimator also may be used to improve resolution and assign the hot spot.