Ionization is the process of converting an atom or molecule with no electrical charge into an ion by adding or removing charged particles such as electrons or other ions, through high temperatures, electrical discharges, radiation etc.

See also Ion.

An accelerator uses electrostatic or electromagnetic fields to increase the kinetic energy of charged particles (see alpha particle, beta particle) in order to produce ionization or a nuclear reaction in a target.
Accelerators (see cyclotron, linear accelerator) are used for the production of radionuclides (see Fluorine-18, Molybdenum, Technetium-99m) or directly for radiation therapy. Accelerator-produced radioactive material (ARM) is any radioactive substance that is produced by a particle accelerator. The accelerators used for radiation therapy generate gamma rays (also called Bremsstrahlung) with continuous energy by collision of high energy electrons on materials with high density (also referred as 'high z' - chemical elements with a high atomic number (Z)).
Electron accelerators with energies above 10 MeV can also produce neutrons induced by photons in the accelerator head material (mainly caused by photo nuclear reaction).

An atom is the basic particle of matter, the smallest (~10^-8cm) particle of a chemical element. Atoms consist of a nucleus with neutrons, positive charged protons and orbiting negative charged electrons. The chemical properties of elements are defined largely by the number of protons in the nucleus. The number of electrons is similar to the number of protons. An atom is ionized when the number of electrons is not equal to the number of protons; the resulting electrical charge depends on the difference between the number of protons and the number of electrons.

See Rutherford-Bohr Atom Model, Ionization.

(CTDI) The computed tomography dose index is most commonly used dose descriptor, which represents the dose to a location (e.g., depth) in a scanned volume.
This index describes the dose from a single rotation of a CT scanner. CTDI must be corrected for pitch or couch increment to receive the dose for a series of slices. The CTDI100 is measured using a 100 mm long ionization chamber. The CTDIair is the value of CTDI determined free-in-air.
Different definitions of CTDI exist and are used in different applications.

Dosage is an important factor in the use of ionization radiation as well as in application of contrast agents or radiopharmaceuticals and the dosage should be comply with the ALARA principle (As Low As Reasonably Achievable).
Ionizing radiation comes from natural and artificial sources. Radiation effects depend on the type of radiation, and various units are used for measurement of dosages including gray, sievert, radiation absorbed dose (RAD), roentgen equivalent in man (REM), and roentgen. The amount of radiopharmaceutical given to a patient is measured in becquerels (Bq).
The dosage of contrast media in radiographic or computer-tomographic procedures should be tailored according to the diagnostic indications, the iodine concentration, and the patient's body size and age.

See also Administrative Dose Guidelines.