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Idiosyncratic Reactions
Patents can unintended respond with an idiosyncratic reaction to the application of contrast media. Idiosyncratic reactions to contrast agents start usually within 20 minutes after injection and occur more frequently in patients 20 to 40 years old.
Idiosyncratic reactions may or may not be dependent on the amount of dose injected, the speed of injection, the mode of injection and the radiographic procedure.

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The minor symptoms are self-limited and of short duration and include:
scattered urticaria, pruritus, rhinorrhea, nausea, vomiting, diaphoresis, coughing, and dizziness.
Patients with minor symptoms should be observed for the progression or evolution of more severe reaction, which requires treatment.
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Intermediate symptoms include:
diffuse urticaria, headache, persistent vomiting, facial edema, laryngeal edema, mild bronchospasm or dyspnea, palpitations, tachycardia, or bradycardia; hypertension; and abdominal cramps.
Intermediate symptoms require treatment and should be observed for progression.
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Severe reactions include life-threatening symptoms:
arrhythmias (ventricular tachycardia), hypotension, overt bronchospasm, laryngeal edema, pulmonary edema, seizures and syncope.
Severe reactions are life-threatening and treatment is urgent and mandatory to prevent death.

See also Adverse Reaction and Anaphylactoid Reaction.
  Further Reading:
Basics:
  • Anaphylaxis
    Thursday, 9 April 2009   by en.wikipedia.org    
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 [last update: 2023-11-06 02:01:00]