When invented, a fluoroscopic system consisted of x-ray tube, fluorescent screen and x-ray table. In 1950's, the development of the image intensifier revolutionized fluoroscopes. The basic components are extended by a gantry, image intensifier, camera, film and monitor system. The x-ray tube is usually located under the patient table, in opposition to the image intensifier and film cassette or display unit. The patient table can be rotated to an upright position for certain examinations and can be lowered to horizontal position for other imaging procedures. In some instances, the unit can be operated from outside the room.
Today, the transition from conventional to digital fluoroscopy replaces the image intensifier. A flat-panel detector in combination with sensitive image sensors and digital image processing improves the diagnostic ability of a modern system.

A myelography is a radiographic imaging procedure to visualize the spinal canal, the spinal cord, cerebrospinal fluid (CSF), intervertebral disks and nerve roots. A special contrast agent (dye) is injected through a needle into the subarachnoid space of the spinal canal. A myelogram provides a very detailed picture of the spinal cord and spinal column. A fluoroscopy displays the bones and the fluid-filled space of the spine also in motion. An additional computerized tomography (CT or CAT) scan helps to differentiate the spinal conditions better. The indications include disc herniation, spinal stenosis, tumor, and vertebral fracture.

See also Myeloscintigraphy, Fluoroscopic System, Hounsfield Unit, Bone Densitometry, Nonionic Contrast Agents.

A fluoroscope projects x-ray images in a video sequence (movie) onto a screen monitor.
Early generation fluoroscopes presented particularly difficult viewing challenges for radiologists. The human retina contains two types of image receptors. Cones (central vision) operate better in bright light, while rods (peripheral vision) are more sensitive to blue-green light and low light. Therefore, the radiologists wear red goggles to filter out blue-green wavelengths to allow the rods to recover peak sensitivity before viewing fluoroscopic images.
To avoid this time consuming accommodation, the industry developed the image intensifier tube in the 1950s. Due to the high amount of individual images during a fluoroscan, a very sensitive amplifier is needed to cut down radiation exposure. Until today, image intensifiers amplify the faint light emitted by the fluorescing screen and the images can be viewed on a monitor. Recently, digital technique replaces the large and bulky image intensifier with flat-panel technology.
Various other components of a fluoroscope system include a gantry, patient table, x-ray tube, filters, collimators, images sensor, camera and computer, most similar to other radiographic systems.
A fluoroscopy system provides the view of moving anatomic structures and is valuable in performing procedures that require continuous imaging and monitoring, such as barium studies, gastrointestinal function tests, cardiac functions, studies of diaphragmatic movement, or catheter placements. A number of technologies are available to record images created during fluoroscopic (fluorographic) exams.

Conventional (also called analog, plain-film or projectional) radiography is a fundamental diagnostic imaging tool in the detection and diagnosis of diseases. X-rays reveal differences in tissue structures using attenuation or absorption of x-ray photons by materials with high density (like calcium-rich bones).
Basically, a projection or conventional radiograph shows differences between bones, air and sometimes fat, which makes it particularly useful to asses bone conditions and chest pathologies. Low natural contrast between adjacent structures of similar radiographic density requires the use of contrast media to enhance the contrast.
In conventional radiography, the patient is placed between an x-ray tube and a film or detector, sensitive for x-rays. The choice of film and intensifying screen (which indirectly exposes the film) influence the contrast resolution and spatial resolution. Chemicals are needed to process the film and are often the source of errors and retakes. The result is a fixed image that is difficult to manipulate after radiation exposure. The images may be also visualized on fluoroscopic screens, movies or computer monitors.
X-rays emerge as a diverging conical beam from the focal spot of the x-ray tube. For this reason, the radiographic projection produces a variable degree of distortion. This effect decreases with increased source to object distance relative to the object to film distance, and by using a collimator, which let through parallel x-rays only.
Conventional radiography has the disadvantage of a lower contrast resolution. Compared with computed tomography (CT) and magnetic resonance imaging (MRI), it has the advantage of a higher spatial resolution, is inexpensive, easy to use, and widely available. Conventional radiography can give high quality results if the technique selected is proper and adequate. X-ray systems and radioactive isotopes such as Iridium-192 and Cobalt-60 for generating penetrating radiation, are also used in non-destructive testing.

See also Computed Radiography and Digital Radiography.

Fluoroscopy is used to study moving body structures in real time. A fluoroscope is used to produce a continuous (advanced fluoroscopy machines provide pulsed techniques to lower the amount of radiation) x-ray beam, passing through the body part being examined and transmitted to a monitor so that dynamic images of deep tissue structures can be visualized. Fluoroscopy is primarily used for gastrointestinal exams, genitourinary studies, cardiovascular imaging and for invasive procedures performed by interventional radiologists and angiographers under fluoroscopic guidance. Fluoroscopy can also produce a static record of an image formed on the output phosphor of an image intensifier. The image intensifier is an x-ray image receptor that increases the brightness of a fluoroscopic image by electronic amplification and image minification. Modern fluoroscopy systems combine less radiation with better image quality due to digital image processing and flat-panel technology.
Roentgen's discovery of x-rays related directly to fluoroscopy, because fluorescence on the material in the room draws his attention to the x-ray's properties. In 1896, Thomas A. Edison created the first fluoroscope, consisting of a zinc-cadmium sulfide screen that was placed above the patient's body in the x-ray beam and provides a faint fluorescent image. In first-generation units, the exam room required complete darkness. The users wear red goggles for up to 30 minutes prior to the examination, to adapt the eyes to darkness. After this, the radiologist stared directly at a yellow-green fluorescent image through a sheet of lead to prevent the x-ray beam from striking the eyes.