A coronary angiogram (or cardiac catheterization) is the radiographic visualization of the coronary arteries after the introduction of a contrast agent. A coronary angiography can be performed for both diagnostic and interventional (treatment) purposes.
A catheter, inserted into a major blood vessel has to be maneuvered up to the coronary arteries to inject a blood compatible iodinated contrast material (dye). The x-ray visible catheter allows injecting a small amount of contrast agent selectively in the coronary arteries or the heart chambers. Continuous images are recorded (movies or cineangiogram) in multiple views from different angles are in order to ascertain the precise location and severity of coronary artery blockages. Digitized images are also saved on computer and replayed onto a video screen as needed.
A coronary angiogram is more invasive and requires more patient recovery time than coronary CT angiography. In the past, the gold standard for detecting atherosclerotic plaque was a coronary angiography and intravascular ultrasound. Today, the American Heart Association considers CT scanning to be one of the most effective, non-invasive methods for the detection of calcification in the coronary arteries.

See also Interventional Radiology.

The industry standard of computed tomography (CT) contrast media power injectors changed over time from single-head to dual-head systems. The advantage of a power (or pressure) injector with two syringes is that a saline solution can be injected first to open the veins, followed by a second injection with contrast agent. Then the first head flushes the saline to maintain contrast flow. As a result, much less contrast agent is needed (about 30 percent less), helping to reduce costs. Dual-head contrast media injectors also provide greater patient safety by reducing the pressure of the flow rate, helping to prevent damage to the veins.
Contrast delivery is much more controlled and efficient when using a dual-head power injector (also called double-piston injector). Also, these medical devices are required to accommodate the quick imaging times typical for a multi-detector CT scanner.

See also Contrast Media Injector, Single-Head CT Power Injector, CT Power Injector, Multi-Head Contrast Media Injector, Syringeless CT Power Injector.

A dye is usually a coloring agent. In medical imaging the term dye refers to radiopaque material used during x-ray examinations to provide or increase contrast in the different tissues and organs. Dye usually refers to intravenous contrast agents.

See also Contrast Agents.

A myelography is a radiographic imaging procedure to visualize the spinal canal, the spinal cord, cerebrospinal fluid (CSF), intervertebral disks and nerve roots. A special contrast agent (dye) is injected through a needle into the subarachnoid space of the spinal canal. A myelogram provides a very detailed picture of the spinal cord and spinal column. A fluoroscopy displays the bones and the fluid-filled space of the spine also in motion. An additional computerized tomography (CT or CAT) scan helps to differentiate the spinal conditions better. The indications include disc herniation, spinal stenosis, tumor, and vertebral fracture.

See also Myeloscintigraphy, Fluoroscopic System, Hounsfield Unit, Bone Densitometry, Nonionic Contrast Agents.

A nonionic dimer consists of 2 joined nonionic monomers. Nonionic dimers are used as x-ray and CT contrast media.
Nonionic dimers have the lowest osmolarity. These contrast materials contain 6 iodine atoms for every 1 particle in solution (CM ratio=6). Modern CT techniques require fast bolus injections and thus low-viscosity, high-concentration, well-tolerated contrast agents. Nonionic dimers have the highest viscosity, which limits the clinical usefulness. Examples of nonionic dimers are iotrolan (Isovist®) and iodixanol (Visipaque).

See also Contrast Agents.