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Searchterm 'Contrast Agent' found in 5 terms [
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Blood Brain Barrier
The intact blood brain barrier prevents that contrast agents penetrate in the normal brain tissue. If the blood brain barrier is damaged by a malignant tumor, the contrast medium can accumulate within the interstitial tumor tissue due to the alterations in the blood brain barrier permeability. Adjacent normal brain tissue does not contain the contrast agent.
Computed Tomography Enterography
(CTE) Computed tomography enterography is an imaging procedure to evaluate diseases affecting the mucosa and bowel wall of the small intestine. CTE uses oral contrast agents to improve bowel wall visualization. Several studies established that small bowel distention using negative oral contrast agent increases diagnostic performance of some abdomen CT studies.
The multi-detector row CT (MDCT) improves temporal and spatial resolution and 3D imaging processes offer a full examination of the small bowel with surrounding structures, depicting the small bowel inflammation associated with Crohn's disease by displaying mural hyperenhancement, stratification, and thickening.
CT enterography versus capsule endoscopy provides a non invasive study with comparable sensitivity, high specificity and overall accuracy.

See also Colonoscopy and Virtual Colonoscopy.
Conray®
Conray® is a contrast agent intended for intravascular administration as a diagnostic radiopaque medium. Conray® is rapidly transported through the circulatory system to the kidneys and is excreted unchanged in the urine by glomerular filtration.
See also Ionic Contrast Agents, Contrast Media Injector, Dual-Head CT Power Injector, CT Power Injector.

Drug Information and Specification
NAME OF COMPOUND
Iothalamate sodium
DEVELOPER
Mallinckrodt, Inc.
INDICATION
Brain and body computed tomography, urography, angiography
APPLICATION
Intravascular
PHARMACOKINETIC
Renal excretion
CHEMICAL BOND
2300 mosm/kgH2O
IODINE CONCENTRATION
400 mg/mL
1.5 mL/kg
PREPARATION
Ready-to-use product
STORAGE
Store below 30°Celsius (86°Fahrenheit)
PRESENTATION
50 mL vials, 50 mL prefilled plastic syringes
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!
Contrast Enhanced Computed Tomography
(CECT) Contrast agents are used during contrast enhanced computed (or computerized) tomography examinations to highlight specific tissues and parts of the body. Bones can be clearly seen on x-ray images, the visualization of some other organs and soft tissues is more difficult. Sufficient contrast is important in perceiving a difference in the density between areas of a CT image. The identification of a disease may be challenging due to very low contrast between pathological tissues (for example tumors, metastases and abscesses), normal organ structures and surrounding tissues.
Contrast agents are used in CT angiography (CTA) to delineate vessels, in multiphasic CT studies to provide dynamic information of blood supply (e.g., liver CT) and in CECT studies of various body parts to achieve opacification of tissue of interest (e.g., kidney CT) in relation to the background tissue. Contrast enhanced multi-detector row CT (MDCT) replaces several conventional diagnostic imaging methods such as intravenous urography, cholangiography, or catheter angiography, due to advanced CT studies with fast examination times, high contrast enhancement, perfusion measurement and multiplanar reformatting capabilities.
See also Contrast Media Injector, Single-Head CT Power Injector, Multi-Head Contrast Media Injector, Syringeless CT Power Injector, CT Power Injector.
Contrast Media Injector
Contrast media injectors are part of the medical equipment used to deliver fluids in examinations such as CT, MRI, fluoroscopy and angiography. Many of these diagnostic imaging procedures include the administration of intravenous contrast agents to enhance the blood and perfusion in tissues.

Mainly there are two types of injector technology:
Piston-based systems use a plunger/piston to move a piston in the cylinder of a reservoir, which works in two directions to first fill the reservoir and then deliver the fluid from the reservoir to the patient, similar to a hand-held syringe.
Peristaltic-pump-based systems operate as rotary pumps that use rollers to compress sections of flexible tubing, drawing fluid directly from the supply source and delivering it to the patient.

See also Single-Head Contrast Media Injector, Dual-Head CT Power Injector, Syringeless CT Power Injector.

The use of x-ray contrast agents in computed tomography (CT) began with a hand injection by the radiologist in the scan room. During its history, CT scanners have made great improvements in speed and image quality. Actual CT systems with multiple detectors allow scan times of a few seconds per body region. Some CT protocols require multiphase scans, where a body region is imaged with a single bolus of contrast in different blood flow phases. Automatic power (pressure) contrast media injectors are required to provide precise control of flow rate, volume and timing of injection. The use of a saline bolus following contrast administration reduces the volume of contrast required.

Most relevant topics for the use of a power injector in medical imaging procedures such as contrast enhanced computed tomography (CECT):
Avoidance of microbiologic contamination;
workflow efficiency in the use of the contrast media injector;
contrast cost and waste volume;
reimbursement.

Must have basic injector control options:
Flow rate with a usual range from 0.1 to 10 mL/sec in 0.1 mL/sec increments; some injectors can be set to inject in ml/min or ml/hour;
volume range from 1 mL to 200 mL for contrast and saline phases;
pressure limit typically programmable from 50 psi to 300 psi in 1 psi increments (also displayable in kPa and kg/cm²).

Examples of other injector control options:
Warmer/heater; an increase in temperature of the contrast medium results in a decrease in its viscosity; warmed contrast media are less viscous and offer lesser resistance;
pre-filled syringes; the compatibility with many selected syringes makes it easy to change and select the appropriate contrast medium for each patient;
injection reports accessible via RIS/PACS for dose management systems and records of prior injections.

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 [last update: 2023-11-06 02:01:00]