The attenuation of radiation is a decrease in intensity as a result of interactions by transmission through matter. X-ray beams attenuate due to photon absorption by the material or scattering. Both effects are energy dependent. The probability of absorption or scattering is a function of the photon energy. The photoelectric absorption is much more energy dependent than the Compton scatter effect.

See also Attenuation Correction, Linear Energy Transfer, Broad Beam and Ion Beam.

(AC) The attenuation correction is usually applied to achieve count rate values independent from tissue densities.

(H) The Hounsfield scale displays radiodensity in a linear scale of gray shades expressed in Hounsfield units (HU). The Hounsfield scale is a quantitative transformation of the attenuation coefficient.
The Hounsfield value -1000 is defined as the radiodensity of air, 0 H that of distilled water at standard pressure and temperature, and denser tissues like for example cranial bone can reach 2000 H. The radiation attenuation of dental fillings or artificial implants depends on atomic number of the elements used. Titanium usually has an amount of +1000 HU. Iron steel can have a density greater than the highest range (traditional 3095 H) covered by the standard Hounsfield scale of a CT scanner. Areas with attenuation coefficients that exceed the scale's maximum are white areas in which no detail is visible.
Some CT machines are relatively tolerant, precise representing regions with very high densities. Sometimes, an option is available to select an extended CT number scale.

The x-ray absorption is the uptake of energy or the decrease of the number of photons by the tissue or matter through which the radiation travels.
Absorption in nuclear reactions and particulate radiation is a process of taking up kinetic energy of particles or the combination of particles with an atom, a nucleus, or another particle.
Absorption characteristics of imaged tissues are represented by their linear attenuation coefficients.

See also Absorber.

The molecular structure of some iodinated contrast agents makes them suitable for the computer-tomographic examination of the biliary tract. Organic iodine compounds increase the attenuation of x-rays and the contrast between body tissues containing iodine and those tissues that do not contain iodine. The degree of opacification is directly proportional to the concentration and volume of the iodinated contrast agent (the total amount of iodine).
Biliary contrast agents can be taken orally, for example calcium iopodate, or intravenous meglumine iotroxate. The contrast media are excreted by the liver and concentrate in the gallbladder after passing the intrahepatic biliary tree and cystic duct.
Oral biliary contrast agents usually opacify the gallbladder after a few hours. If the gallbladder is removed, an intravenous cholegraphic agent is required and gallbladder CT can start 60 minutes after the beginning of contrast medium infusion.
The main limitation of the use of biliary contrast agents is the high rate of allergic reactions and of renal or hepatic toxicity. Caused by the potential for systemic toxicity with intravenous cholangiography, ultrasonography should be the preferred method for evaluation of the gallbladder and the bile ducts.